The present disclosure provides a method for route release in Computer Interlock (CI). The method includes: judging whether a train normally drives into a current locked section; if a judging result is yes, judging whether the train drives away from the current locked section; if a judging result is yes, judging whether a rear section of the current locked section is released; and if a judging result is yes, releasing the current locked section. According to the present disclosure, whether the train normally passes through the locked section can be accurately determined, and no misjudgment occurs, thereby ensuring driving safety. Further provided are an apparatus for route release in CI, and a computer storage medium.