The invention discloses an air purifying device with circularly replaced filter elements, which comprises a quadrangular body. An air inlet layer, a fan layer and a filter layer are sequentially arranged on the quadrangular body from bottom to top; air inlet holes are uniformly distributed in an outer wall of the air inlet layer; the bottom part of the air inlet layer is sealed; a rubber base is arranged; a fan for extracting air is arranged in the fan layer, so that outside air enters from the air inlet holes, penetrates through fan blades and enters the upper-layer filter layer. According tothe device provided by the invention, multiple filter elements are arranged in the filter layer in a stacking way, the air upwards moves from the filter element at the lowest part and is purified through multiple layers of filter elements, and after replacement, the filter element at the bottommost layer is extracted, and a layer of new filter element is added on the topmost layer, so that the filter element at the bottom layer is ensured to be circularly replaced and utilized, the utilization rate is sufficient, the topmost layer can be ensured to be provided with a new filter element aftereach-time replacement, an air purification effect of the air can be ensured, and the production of the cleaned air is ensured.