The invention discloses a bioelectricity impedance signal generation method and a simulation device. The method includes the steps of 1, modeling of bioelectricity impedance signals; 2, generation ofdigital signals; 3, generation of impedance signals and capacitive reactance signals; 4, conversion between impedance and capacitive reactance; 5, synthesis of the bioelectricity impedance signals. The simulation device includes an upper computer or a microprocessor, a digital control resistor, a digital control capacitor, an impedance conversion circuit, a capacitive reactance conversion circuitand a synthesis circuit. The method and device solve the problems that the bioelectricity impedance signals are unstable, vary as time and have a cycle period, chaos and obvious individual differences. The problem that the prior art cannot meet demands of instrument design, production, debugging, calibration and animal experimental tests at the same time is also solved. The problem that the priorart cannot achieve dynamic simulation of bioelectricity impedance changes in a physiological process or a pathological process is also solved.