The invention discloses a process for preventing hot-rolling edge cracking of oriented silicon steel. The process comprises the steps that the surface temperature of a plate blank is no smaller than 300 DEG C before the plate blank enters a heating furnace; the furnace gas temperature of a first heating section is 1160-1250 DEG C; the furnace gas temperatures of a second heating section and a soaking section are each 1270-1330 DEG C, the heating time is 80-200 minutes, and the standing time is no longer than 30 minutes; the average grain size of the edge of a hot-rolled finished product is nolarger than 72 [mu]m; the final rolling temperature of finish rolling is 880-960 DEG C; the coiling temperature is 500-620 DEG C; and tension of a seven-rack finish rolling unit is reasonably controlled. On the premises that sufficient solid solubility of an oriented silicon steel inhibitor is ensured and electromagnetic performance of the finished product meets the target requirement, the problems that the edge of the plate blank is decarburized or the plate blank is locally decarburized when the heating time of the second heating section and the soaking section is too long or when the standing time is too long, grains grow excessively, and edge cracking occurs in the hot-rolling process are avoided.