The invention discloses pyridinone azo disperse dye containing sulfonate groups and a synthesis method of the pyridinone azo disperse dye. The chemical structural general formula is as follows in formulas (I) and (II) in the description. According to the method, 2-benzenesulfonyloxy aniline or 4-benzenesulfonyloxy aniline is taken as a raw material and is diazotized and coupled with 6-hydroxy-4-methyl-3-cyano-1-substituted-2-pyridone, and a product is obtained. In the formulas, R is a linear alkyl group of 3 to 8 carbons, a branched alkyl group of 3 to 8 carbons, or an alkoxyalkyl group of 3 to 8 total carbons, wherein the alkoxyalkyl group of 3 to 8 total carbons contains 2-alkoxy ethyl, 3-alkoxy propyl and 4-alkoxy butyl. The product is novel in structure, simple to synthesize, low in cost and excellent in performance, and is suitable for industrial production.