The invention discloses a high temperature-resistant nodular cast iron. The high temperature-resistant nodular cast iron comprises, by weight, 2.5-3.5% of carbon, 2.8-3.1% of silicon, 3.5-4.5% of aluminum, 0.1-0.5% of vanadium, 0.05-0.1% of boron, 0.03-0.04% of magnesium, 0.1-0.2% of copper, 0.3-0.4% of phosphorus, 0.13-0.2%of chromium, 0.2-0.4% of manganese, 0.5-0.7% of molybdenum, 0.2-0.3% of cadmium, and the balance of iron. The high temperature resistance of a nodular cast iron piece is significantly improved by optimizing the composition and the proportion of the nodular cast iron. The nodular cast iron has a good casting performance and a good machining performance; and a preparation method of the nodular cast iron has the advantages of reasonable design and easy control in technologic conditions, and facilitation of the production of the casting.