The invention belongs to the array signal processing technical field and relates to a co-prime area array-based two-dimensional direction of arrival quick estimation method. The co-prime area array-based two-dimensional direction of arrival quick estimation method includes the following steps that: of: array manifold matrixes are constructed on the basis of an x-axis and a y-axis respectively according to a co-prime area array model, two uniform sparse area arrays are combined so as to form the co-prime area array model; the covariance matrixes of the received signals of the sub-arrays are solved, the propagation operator matrixes of the arrays are constructed on the basis of the x-axis and the y-axis; a PM (Propagator Method) is adopted to solve the twiddle factor matrixes of the sub-arrays along the x-axis and y-axis on the basis of block processing performed on the array manifolds; and angle ambiguity is eliminated through using the co-prime theory of planar arrays, and the azimuthsand pitch angles of the arrays are solved. With the method of the invention adopted, low-complexity, high-precision and fuzzy-free joint estimation of the pitch angles and azimuth angles under the co-prime area array model can be realized.