The invention provides a tooth filling resin material. The material is prepared from, by weight, 15-30 parts of polyvinyl chloride resin, 5-11 parts of amine modified epoxy acrylate, 6-10 parts of dodecyl amine oxide, 15-18 parts of hydroxyethyl polymethacrylate, 2-5 parts of fimbrin, 10-11 parts of glycosaminoglycans, 10-12 parts of cystine diethyl ester, 1-3 parts of silver 4-cyclohexylbutyrate,4-6 parts of nanometer silver powder, 5-7 parts of paeonol, 10-12 parts of antioxidant, 5-6 parts of nanometer filler, 2-3 parts of stabilizer and 15-20 parts of double distilled water. The tooth filling resin material has the excellent surface hardness and the good wear resistance, surface polishing treatment is performed easily, the tooth filling resin material contains no heavy metal, and thetooth filling resin material is environmentally friendly; the preparation method is simple and easy to implement.