The invention relates to an iron-containing titanium alloy pipe for high corrosive oil and gas development and a preparation method thereof, and solves the problems of high cost, processing complexityand large performance gap of a conventional titanium alloy pipe; besides containing Ti, the iron-containing titanium alloy pipe mainly consists of the following components according to the mass percentage: 5.8-6.4% of Al, 2.4-3.0% of V, 0.6-1.2% of Fe, 0.02-0.06% of Ru, 0.05-1.3% of Ni, not more than 0.2% of O, not more than 0.04% of C, not more than 0.04% of N, and not more than 0.0135% of H. Meanwhile, the invention also provides a preparation method for the titanium alloy pipe. A titanium alloy pipe material adopts reasonable alloy composition design, the usage amount of precious metals Ruand V and the like in the original composition is reduced, beta-phase stabilizing elements are supplemented with reasonable Fe and O element ratio, the strength and toughness of the alloy are improved, and with use of the synergistic effect of the elements such as Ru, V, Fe, Ni, W and Mo, the cathodic hydrogen evolution reaction rate of a titanium alloy surface can be improved and the surface oxide film is kept dense and stable to improve the corrosion resistance.