The invention provides a full-automatic bead stringing machine. The full-automatic bead stringing machine comprises an arranging and feeding structure, a wire feeding structure and a bead stringing structure; the arranging and feeding structure comprises a vibration queuing and sorting component and a following process receiving tank; the wire feeding structure comprises a wire feeding bracket, areel, a wire supply mechanism and a bead pressing mechanism, the wire supply mechanism is provided with a wire biting roll layer, a drive roll layer and a wire drawing roll layer; the bead stringing structure comprises a left covering component and a right covering component which are matched with each other, the left covering component comprises a plurality of left traction blocks arranged in a straight line, a plurality of left cushion blocks, a plurality of left guide blocks and a plurality of left pressing blocks, and the right covering component comprises a plurality of right traction blocks arranged in a straight line, a plurality of right cushion blocks, a plurality of right guide blocks and a plurality of right pressing blocks. The full-automatic bead stringing machine fully automatically strings the beads, the scattered beads are discharged from the arranging and feeding structure to the bead stringing structure, and the lead wire led out form the wire feeding structure also enters the bead stringing structure and moves along a stringing channel, so that the bead is stringed, the degree of automation is high, and the bead stringing efficiency is high.