The invention discloses a radioactive sample activity multipath automated measurement system. The system comprises a sample band bracket device, a motion control module, a shielding lead chamber, a measurement module, a digital multi-channel analysis module, a serial communication module and a PC; the motion control module is connected with the sample band bracket device to control the movement ofthe sample band bracket device; the measurement module is connected with the digital multi-channel analysis module to output detection data and is used for detecting the radioactivity of samples; andthe PC outputs control signals to the sample band bracket device, the motion control module and the serial communication module and receives acquired data output by the digital multi-channel analysismodule. The radioactive sample activity multipath automated measurement system has the advantages that the radioactive activity of a large number of active samples can be measured rapidly, multiple detectors can automatically measure 5 paths of sample bands simultaneously, and each path of sample bands can be automatically controlled and moved; and the problem of measuring errors caused by the individual differences of different detectors can also be solved.