The invention discloses a personnel airlock linkage mechanism. The personnel airlock linkage mechanism comprises an inner door control module and an outer door control module; the inner door control module and the outer door control module each comprise an input shaft, a clutch, a control component and a linkage part connected with the control component; each input shaft is connected with the corresponding control component through the corresponding clutch and provides power for the control component in the engagement process of the clutch; and the linkage part of the inner door control modulecontrols action of the clutch of the outer door control module, and the linkage part of the outer door control module controls action of the clutch of the inner door control module. When an outer door is opened, the clutch of an inner door is disengaged; and when the inner door is opened, the clutch of the outer door is disengaged. With the adoption of the mode of controlling engagement and disengagement of the input shafts, the clutches are disengaged when linkage is needed, then transmission components cannot act instead of getting stuck, the transmission components are effectively protected while the linkage function is achieved, component damage caused by misoperation of personnel is avoided, and the safety and reliability are improved.