The present disclosure discloses a deep brain stimulation system having k focuses, which comprises: a first electrode and a second electrode, used for connecting one side of a brain scalp; a third electrode and a fourth electrode, used for connecting the other side of the brain scalp; and a first signal generation unit, a second signal generation unit, . . . , a (2k−1)th signal generation unit and a 2kth signal generation unit, wherein the k is a positive integer greater than or equal to 2; and each of the signal generation units is used for providing the following currents for the first electrode to the fourth electrode: a first current and a second current, which are interfered at a deep portion of a brain to form a first focus; and a (2k−1)th current and a 2kth current, which are interfered at the deep portion of the brain to form a kth focus; for the first current, the second current, . . . , the (2k−1)th current and the 2kth current, each of the currents is a sine wave of which the peak-to-peak value is unchanged all the time; and from the first focus to the kth focus, the interference of the currents is not occurred therebetween. Through the above technical solution, the deep brain stimulation system can perform simulation of two focuses and more on the deep portion of the brain and can be used in simulation research or a therapeutic field; and when being used in the therapeutic field, the deep brain stimulation system has the characteristic of non-invasion.