The invention relates to a silane modified polyether hot melt adhesive composition. 100 parts of the silane modified polyether hot melt adhesive composition mainly comprises a component A composed of,by weight, 25 to 60 parts of one or a plurality of kinds of alkoxy terminated alpha-silane modified polyether prepolymers, a component B composed of, by weight, 30 to 65 parts of one or a plurality of kinds of inorganic filling materials, a component C composed of, by weight, 3 to 30 parts of a tackifying resin, a component D composed of, by weight, 0.2 to 10.0 parts of one or a plurality of kinds of organic thixotropic agents, a component E composed of, by weight, 3 to 30 parts of a plasticizer, and a component F composed of, by weight, 0.5 to 6.0 parts of one or a plurality of silanes, wherein at least one ingredient of the component F is of an amino-terminated structure. In applications, the silane modified polyether hot melt adhesive composition is heated to 80 to 120 DEG C, is especially suitable for bonding of metal, plastic, or paint sprayed surfaces; after adhesive construction, primary adhesive force is achieved in an extremely short time period, and secondary solidificationis realized under the action of moisture; the silane modified polyether hot melt adhesive composition is extremely suitable of increasing of production efficiency, contains no heavy metal catalyst, and is good for both health and the environment.