The invention discloses a method for compounding chiral nonaromatic purine nucleoside through [3+2] cycloaddition asymmetric aromatization and belongs to the field of asymmetric synthesis in organic chemistry. Purine and aminocyclopropane dicarboxylic acid methyl ester are taken as raw materials and have catalytic reaction under the condition of lewis acid, and then the chiral nonaromatic purine nucleoside is acquired. The invention provides a simple, convenient, low-cost and high-efficient method for compounding chiral nonaromatic purine nucleosides; the raw materials for reaction are easilyacquired; the product structure is abundant; maximal reaction enantioselectivity can reach up to 99%; maximal yield can reach up to 98%.