The invention discloses a high-precision dissolved oxygen detection device. The device comprises a dissolved oxygen detection circuit, a radio transmission and receiving module, a control chip, a liquid crystal display storage module and a power supply module, wherein the dissolved oxygen detection circuit comprises a dissolved oxygen sensor group and a signal regulating circuit, and is used for calculating the content of dissolved oxygen through output current of the detection circuit; the radio transmission and receiving module is used for uploading data and modifying running parameters; thecontrol chip is used for collecting signals output by the dissolved oxygen detection circuit in real time, and analyzing and calculating data; the liquid crystal display storage module is used for displaying and storing calculated data; the power supply module is used for supplying power to each module of the dissolved oxygen detection device; and the control chip is used for acquiring a final value of the dissolved oxygen by analysis and calculation of multiple groups of collected data and compensation operation of liquid temperature. According to the high-precision dissolved oxygen detection device, the detection precision of the liquid dissolved oxygen content is improved by structure improvement and algorithm optimization of the dissolved oxygen detection device, and the data reliability can be enhanced.