The invention discloses A novel automobile wire harness protection structure Including a car wiring harness, a Butted wiring harness insert and a protective rubber sleeve, At least two strand of single cable are twisted into that automobile wire harness, each cable comprises a winding cladding layer wound around the conductor and an insulating layer squeezed around the winding cladding layer, Theouter surface of the branch node of the automobile wire harness is coated with a PVC covering, the PVC covering is a polyvinyl chloride sheet, and the protective rubber sleeve is composed of a mounting port, a wire harness guide tube, a shock absorbing tube and a wire harness connecting port which are connected in turn, and the mounting port is in the shape of a bell mouth. The wiring harness guide tube of the protective rubber sleeve matches with the shape and the installation angle of the wiring harness insert, so that the wiring harness is smoothly and transitionally bent, and the stress isavoided to be too tight; The U-grooved wiring harness connector facilitates fixing of the wiring harness and wiring harness bellows.