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发明公开
CN109134490A 延命草素型二萜硫化氢供体衍生物及其制备方法和用途 有权

延命草素型二萜硫化氢供体衍生物及其制备方法和用途
摘要：
本发明涉及天然药物及药物化学领域，具体涉及延命草素型二萜的14‑OH拼合硫化氢供体衍生物。还涉及这些在延命草素型二萜的14‑OH拼合硫化氢供体衍生物的制备方法和在制备抗肿瘤药物中的应用。所述的延命草素型二萜的14‑OH拼合硫化氢供体衍生物及其药学上可接受的盐具有式I或式II的结构：其中，n为0‑12的整数。
摘要（英）：

The invention relates to the field of natural medicine and medicinal chemistry, in particular to enmein-type diterpene 14-OH spliced hydrogen sulfide donor derivatives, as well as their preparation method and application in the preparation of antitumor drugs. The enmein-type diterpene 14-OH spliced hydrogen sulfide donor derivatives and their pharmaceutically acceptable salts have a structure of formula I or II (shown in the description), wherein n is an integer of 0-12.

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