The invention discloses a fatigue detection method based on information of key points of eyebrows and eyes, which comprises the following steps: 1, acquiring a driver's face image; 2, obtaining the opening and close degree between the eyebrows and the eyes of the driver; 3, judging driver fatigue state. The method is used for judging the opening and closing degree between eyebrow and eye, and fordetecting the eye opening and closing state.