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发明公开
CN109337978A miRNA在制备高级浆液性上皮性卵巢癌化疗耐药性评价试剂盒中的应用 审中-实审

miRNA在制备高级浆液性上皮性卵巢癌化疗耐药性评价试剂盒中的应用
摘要：
本发明涉及miRNA在制备预测高级别浆液性卵巢癌铂类化疗耐药性的诊断试剂中的应用，所述的miRNA包括miR-1287，miR-3131，miR-335，miR-4419，miR-4468，miR-96，并提供了基于测定miR-1287，miR-3131，miR-335，miR-4419，miR-4468，miR-96的表达量的来分析检测高级别浆液性卵巢癌铂类化疗耐药性的应用，该应用较现有的预测高级别浆液性卵巢癌铂类化疗耐药性的方法具有更好的准确性。
摘要（英）：

The invention relates to application of miRNA in preparation of a diagnostic reagent for predicting platinum chemotherapy drug resistance of high-grade serous ovarian cancer. The miRNA comprises miR-1287, miR-3131, miR-335, miR-4419, miR-4468 and miR-96. The invention also provides application for analyzing and detecting platinum chemotherapy drug resistance of high-grade serous ovarian cancer onthe basis of the determination of the expression quantity of miR-1287, miR-3131, miR-335, miR-4419, miR-4468 and miR-96, and the application has better accuracy than the existing method for predictingplatinum chemotherapy drug resistance of high-grade serous ovarian cancer.

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