The invention relates to an anti-sequence-leakage off-by-one counting and synchronous zero clearing control system for a robot production line, comprising an image collection module, a data processingmodule, a storage module and an image comparison module. The image collection module collects the target image information of the welding positions of the same product in the process in which a robotcarries out welding at the welding positions in turn according to a preset welding program. The image comparison module is used for acquiring the target image information of the welding positions collected by the image collection module in turn and comparing the target image information of the welding positions with pre-stored image information in the storage module in real time to judge whetherthere is wrong or missing welding. The data processing module is used for acquiring a judgment result generated by the image comparison module in real time and judging whether the robot pauses according to the judgment result. The detection result is reliable and stable. Detection is fast and can be carried out for a long time, and detection for 24 hours a day is realized.