The invention discloses an injection mold of a multi-color spectacle frame, and relates to the technical field of injection molds. According to the technical scheme, the injection mold comprises an upper mold and a lower mold, a hot runner and a positioning cavity for containing spectacle legs are arranged between the upper mold and the lower mold, the upper mold and the lower mold are provided with cavities for forming different-color parts of a non-slip section and a bending section, and the hot runner communicates with the cavities. The upper mold is provided with an injection port for injection molding of an injection molding machine, the injection port is in communication with the hot runner, and the length direction of the hot runner in the upper mold is in the vertical direction. The lower mold is provided with a first spring, and clamping portions are slidably arranged on the two sides of the positioning cavity. Compared with the paint spraying coloring method, the shape and the position of different-color layers formed by injection molding are accurate, irrelevant parts are not prone to being sprayed, manual spraying is not required, and the manual workload is reduced; andthe positioning accuracy of the spectacle legs in the lower mold is high, the stability is high, and the plastic molding quality can be ensured. The quality of the spectacle frame produced by the injection mold is better.