The invention belongs to the technical field of moulds, and particularly relates to an implantation-grade sensor monitoring probe. The implantation-grade sensor monitoring probe is used for placing atemperature sensor and a pressure sensor. The monitoring probe comprises a shell; a cambered in-going opening is formed in the front end of the shell; a pipe opening is formed in the rear end of the shell; a rectangular groove is formed inwards in the middle of the shell; a metal bonding pad is arranged on the bottom of the rectangular groove through sputtering; a cavity with the shape identical to that of the shell is formed between the rectangular groove and the pipe opening in the rear end of the shell. The probe is made from a PEEK material with biocompatibility, and while the functions ofa conventional titanium alloy shell are met, the probe making process difficulty is greatly reduced; the probe is made by using an opening mould, so that the production cost is greatly reduced. Besides, the PEEK material is insulated, the risks of sensor encapsulation and short circuit of electrodes and wires in the using process are reduced, and the electric safety factor of an implanted part isimproved.