The invention relates to a tofacitinib citrate oral solution, in particular to a tofacitinib citrate oral solution with more stable pharmaceutical properties and a preparation method of the tofacitinib citrate oral solution. The tofacitinib citrate oral solution is prepared from tofacitinib citrate, a pH regulator, a preservative, a flavoring agent and water. The tofacitinib citrate oral solutionhas better stability and is suitable for children and old people with dysphagia.