The invention discloses a digital electro-hydraulic loading device suitable for a large load interval. The digital electro-hydraulic loading device suitable for the large load interval comprises a hydraulic cylinder group, a guide mechanism, a loading mechanism and a loading control loop, wherein the acting areas of the hydraulic cylinder group, the guide mechanism, the loading mechanism and the loading control loop increase progressively according to the geometric progression; the hydraulic cylinder group is connected with the loading mechanism through the guide mechanism to transmit loadingforce to the loading mechanism. The hydraulic cylinder group comprises a hydraulic cylinder controlled by an electro-hydraulic proportional valve or an electro-hydraulic servo valve and (N-1) hydraulic cylinders controlled by a common on-off valve, wherein N is a positive integer greater than 1, and by controlling the pressure of the electro-hydraulic proportional valve or the hydraulic cylinder controlled by the electro-hydraulic servo valve under different load values and the opening or closing state of the hydraulic cylinders controlled by the common on-off valve, the continuous change of the total output loading force in a certain full range is achieved. The digital electro-hydraulic loading device suitable for the large load interval does not need to adopt the large hydraulic cylinderand a hydraulic system matched with the large hydraulic cylinder, so that the problems of increased manufacturing cost, slow response of the system and poor dynamic performance of the system are solved.