The invention discloses a vehicle-mounted reinforced measurement and control encryption and decryption machine, and belongs to the field of spacecraft engineering. According to the invention, a software and hardware system of the vehicle-mounted measurement and control encryption and decryption machine is subjected to reinforced design; the hardware system comprises a high-integration master control module, a safety control module, a storage module, a display interface module, a power module, a network interface control module, a state alarm module, a case, an external interface and the like.The software system comprises a network communication module, a main and standby monitoring module, a hardware interface module, a configuration information management module, a system internal control module, a security management module and a task processing unit module. The problem that existing vehicle-mounted measurement and control encryption and decryption machines cannot adapt to vehicle-mounted systems with more complex users and more severe application environments is solved, and the encryption and decryption machine improves the stability and safety of vehicle-mounted encryption anddecryption machines, is suitable for development of vehicle-mounted reinforced measurement and control encryption and decryption machines, and has good popularization value.