The invention discloses a leafy vegetable atomizing cultivation device, which comprises a cultivation system, a nutrient solution atomizing reflux system, a temperature and humidity control system, anillumination control system, a carbon dioxide supply system and an airflow circulation system, wherein the cultivation system comprises a plurality of cultivation pipes arranged in the box body; thenutrient solution atomizing reflux system comprises a nutrient solution storage groove, an ultrasonic sprayer, a nutrient solution conveying pipeline, an aerosol pipeline and a reflux pipeline; the temperature and humidity control system comprises a hot and cold air conditioner, an atomizing machine and a temperature and humidity sensor; the illumination control system comprises a plant growth lamp and an illumination intensity sensor; the carbon dioxide supply system comprises a carbon dioxide steel cylinder, a conveying pipeline and a carbon dioxide sensor; and the air circulation system comprises an axial flow ventilation fan. The temperature, humidity, illumination intensity, carbon dioxide concentration and the like in the whole process of seedling raising and growth of leafy vegetables can be automatically adjusted, control is carried out according to the actual growth condition of the leafy vegetables, and the growth of the leafy vegetables is accelerated.