The invention relates to an automatic nail driving method of a liquefied natural gas ship heat insulation wooden box. The automatic nail driving method includes the following steps that firstly, multiple user coordinate systems are defined according to nail driving work positions; secondly, coordinate origins and coordinate systems of all faces of the insulation box are defined; thirdly, the naildistance numerical value is adopted as the coordinate offset corresponding to the user coordinate systems of a robot; fourthly, the work starting points of moving of the robot on all insulation box nail driving faces are defined; fifthly, nail distance coordinate offset registers are arranged in a robot controller; sixthly, nail distance coordinate compensation registers are arranged in the robotcontroller; and seventhly, a nail gun is installed on a six axis of the nail driving robot, an insulation box fixing tray moves to the nail driving positions of the robot to stop moving, and the naildriving robot automatically runs according to a nail driving track automatic adjusting method till nail driving on all the work faces is completed. Compared with the prior art, the automatic nail driving method has the beneficial effects of being clear in logic and easy and convenient to control, multi-mode adjustment strategies are achieved, and the nail driving quality is high.