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发明公开
CN110331187A 组合标签、组合标签接头及其应用 审中-实审

组合标签、组合标签接头及其应用
摘要：
本发明涉及基因测序领域，具体涉及一种组合标签、组合标签接头及其应用。该组合标签包括至少两组标签，所述至少两组标签的每一组含有至少两个标签序列，所述至少两组标签的每一组内任意标签序列间的汉明距离大于等于2，所述至少两组标签的每一组间任意标签序列间的汉明距离大于等于1。该组合标签接头含有接头序列和该组合标签。应用该组合标签或者该组合标签接头进行基因文库的构建、测序等，可以有效避免样本间的污染，提升测序深度。
摘要（英）：

The invention relates to the field of gene sequencing, in particular to a combination tag, a combination tagjoint, and application ofthe combination tagandthe combination tag joint. The combination tagcomprises two or more sets of tags, each set of the two or more sets of tags contains two or more tagsequences, the Hamming distance between any tag sequences in each of the two or more sets of tagsis greater than or equal to 2, the Hamming distance between any of the tag sequences between each of the two or more sets of tags is greater than or equal to 1. The combination tag joint contains a joint sequence and the combination tag. The combination tag or the combination tag jointis used for gene library construction, sequencing and the like, contamination between samples can be effectively avoided,and the sequencing depth is increased.

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