The invention relates to a voice data noise reduction method and device based on artificial intelligence, a computer device and a storage medium. The voice data noise reduction method comprises the steps that a noise reduction request sent by a terminal is received, and corresponding feature combinations of to-be-processed audio data and incidence relations among various features in the feature combination are acquired; the degree of discrimination of each feature combination is calculated according to the relation among features; and the feature combinations are filtered according to a presetdiscrimination degree threshold value, an initial feature combination is obtained, the initial feature combination is filtered by using a preset evaluation index to obtain available feature combinations, the to-be-processed audio data corresponding to the available feature combinations is obtained, first initial audio data based on the discrimination degree is generated, and based on a deep learning noise reduction model, the first initial audio data is subjected to noise reduction processing to generate the noise-reduced voice data. The voice data based on the discrimination degree is subjected to voice reduction by using the deep learning noise reduction model, and the noise reduction effect of the voice data is improved.