The invention discloses a lifting opening and closing device based on a cam mechanism. The device comprises a rack, a lifting opening and closing mechanism and a height adjusting mechanism. The rack comprises an outer frame and a lifting frame, a hole communicating with an inner cavity is formed in the top face of the outer frame, the lifting frame is arranged in the inner cavity of the outer frame and comprises a lifting part and a supporting part, the lifting part and the supporting part are in sliding connection, and the lifting part is located below the hole;the lifting opening and closingmechanism is arranged in the inner cavity of the outer frame, and comprises two plate turning assemblies which are oppositely arranged on the lifting part of the lifting frame, each plate turning assembly is provided with a fixed part and a turnover part, the lower portions of the fixed parts are arranged on the lifting part, the upper portions of the fixed parts are hinged to the turnover parts,and force exertion parts are arranged on the outer sides of the turnover parts;and the height adjusting mechanism is arranged in the inner cavity of the outer frame and comprises a driving motor usedfor transmitting power, a rotating shaft used for transmitting driving force and a cam used for driving a chassis of the height adjusting mechanism to vertically ascend and descend. The lifting opening and closing device has the beneficial effects that space is saved, and opening and closing can be achieved in the small space; andin the opening and closing process, stable opening and closing canbe achieved, and meanwhile, coinciding of the closed plane and the original plane can be achieved.