The invention relates to an inter-frame difference-based driving license printing information integrity detection method, which comprises the following steps of: obtaining a first frame image of a certificate output by a photo printer, and detecting whether human image information exists in the image or not by using a face recognition algorithm for the image; sending the certificate paper containing the portrait information into a character printer for continuous printing, and obtaining an image of the certificate output by the character printer as a second frame image; performing inter-framedifference on the acquired two frames of images to obtain a differentiated image; and detecting whether the differentiated image has printed character information or not, if the differentiated image contains the character information, indicating that the driving license is completely printed, and otherwise, indicating that the driving license information is not completely printed. According to themethod, key feature extraction can be carried out in the two processes of photo printing and character printing in sequence. The requirement of automatic recognition is met, and the accuracy of feature information recognition is also improved.