The invention provides a three-dimensional coordinate frame suitable for positioning a wind tunnel test probe, and belongs to the field of fluid mechanics wind tunnel tests. The three-dimensional coordinate frame comprises a supporting structure, a displacement mechanism, a coordinate control mechanism and a probe support. The supporting structure comprises a plane frame, a vertical beam supporting frame and a switch type magnetic base. The displacement mechanism comprises an X-axis movement unit, a Y-axis movement unit and a Z-axis movement unit. The coordinate control mechanism is used for controlling the specific positions of all the movement units. The windward section of the probe support is a wind type section, and the probe support is fixed to the Z-axis movement unit and used for installing an experimental probe. The three-dimensional coordinate frame is flexible in installing position, simple and rapid after the switch type magnetic base is connected with a tunnel body of a wind tunnel experimental section connected in use and can be rapidly separated from a wind tunnel and moved out of the wind tunnel experimental section without influencing the integrity of the structureof the wind tunnel after being used; the three-dimensional coordinate frame is simple in overall structure and small in windward area and almost has no influences on the inherent flow field characteristics of the wind tunnel; the work efficiency of the wind tunnel experiment can be improved.