The invention discloses a bacillus amyloliquefaciens strain GUTU06 producing various enzymes and a screening method of the bacillus amyloliquefaciens strain GUTU06 producing various enzymes. Natural multienzyme new strains producing nattokinase, proteases, beta-glucosidases, amylases and the like are screened out from traditional fermentation fermented soya beans, soybeans are fermented through the strains to prepare natto, and the prepared natto has the functions of preventing cardiovascular and cerebrovascular diseases, promoting digestion, transforming ginkgo biloba flavonal glycosides andthe like. Besides, a new culture method for producing the nattokinase, the proteases, the beta-glucosidases and the amylases at the same time is provided, and the safety is high. Because the soybeansare extensive in sources and moderate in price, the production cost of the nattokinase, the proteases, the beta-glucosidases and the amylases is reduced. In addition, the invention provides a simple purification method for extracting the nattokinase from fermented soya beans. Therefore, the bacillus amyloliquefaciens has good application prospects.