The invention relates to a strong weathering strong oxidation sand rock uranium ore water smelting method. The method comprises the following steps of only using a crushing process and a screening process to prepare a -1mm sandstone uranium ore sample; carrying out a reagent-free leaching test through stirring on the prepared ore sample; analyzing uranium content of filtrate and tailing residues,and calculating the leaching rate of filtrate meter and residues meter; recovering uranium in the leachate through adopting 201*7 resin; leaching the uranium through adopting NaCl and H2SO4 to obtaina qualified solution; then precipitating the uranium in the qualified solution through using a sheet NaOH to obtain a "111" product; and recycling a precipitation mother solution to prepare a leachingsolution. According to the method, a grinding process of the ore is avoided, closed-loop cyclic utilization of the process solution is realized, and recovery rate of the uranium and purification degree of the product are improved; through adopting the method of reagent-free leaching, utilization of chemical reagents such as sulfuric acid is avoided, no wastewater discharge is realized, the cost is saved, and the environment is protected.