The invention discloses a pipeline clean-up device driven by an electric hand drill. The pipeline clean-up device driven by the electric hand drill comprises a rotating clean-up plate, soft transmission shafts, a connecting shaft and the electric hand drill and is characterized in that a movable arm and a scraper are hinged onto the rotating clean-up plate; one end of each soft transmission shaftis designed into a convex part, and the other end of each soft transmission shaft is designed into a concave shape; the soft transmission shafts are connected through an insertion pin for torque transmission; the number of the soft transmission shafts can be fast increased or deceased; through a plurality of soft transmission shafts, the rotating clean-up plate and the connecting shaft are connected, the torque is transmitted, and the rotating movement is performed; and the connecting shaft is specially designed into a special connector for the electric hand drill, and can be fast, conveniently and reliably connected with the electric hand drill. The pipeline clean-up device provided by the invention can enter a pipeline with a small caliber; the plurality of soft transmission shafts can be connected according to different pipeline length requirements so as to reach different positions; the motor rotating speed of the electric hand drill can be regulated; the centrifugal force is increased; and the clean-up range and effect are increased. The pipeline clean-up device driven by the electric hand drill can be used for cleaning sewage pipelines of residential buildings, and enters thepipeline through a water discharging opening of a sewage pool, and the blockage problem of the pipelines is effectively solved.