The invention provides a safe power-off system of tobacco primary processing equipment. The system comprises a control power supply, a dynamic power supply, a contactor, a control power switch and a dynamic power switch, wherein the contactor and the control power switch are arranged in parallel, an output end of the control power switch is connected with a control end of the dynamic power switch,an input end of the control power switch is connected with the control power supply, an input end of the dynamic power switch is connected with the dynamic power supply, and an output end of the dynamic power switch is connected with a power end of the tobacco primary processing equipment. Through the system, the problem that according to existing tobacco equipment, equipment cooling requires a long time after production is over, the situation that an operator performs power-off directly is prone to occurrence, and consequently the equipment cannot be cooled according to set time is solved, and the intelligence and safety of equipment power supply can be improved.