The invention relates to a method for preparing 2-amino-5-methyl-6-halogenated pyridine. According to the method, 2-halogen-3-methylpyridine nitrogen oxide is taken as a raw material; reaction is carried out under the action of an acid anhydride, an acid-binding agent and an amination reagent in a reaction solvent so as to obtain 2-amino-5-methyl-6-halogenated pyridine, wherein the reaction solvent is a halogenated hydrocarbon; the product 2-amino-5-methyl-6-halogenated pyridine/4-isomer can reach 93/7, the product purity is as high as 99.8% or above, the reaction yield is 70% or above, meanwhile, the method is high in amplification performance and good in process stability, and large-scale industrial production can be achieved.