The invention relates to an on-line automatic spray cleaning system for reconstituted tobacco made by a papermaking method. The cleaning system comprises a liquid storage tank, a stainless steel pipeline, a low-pressure spray water pump, a medium-pressure spray water pump, a manual butterfly valve, a check valve, a steam pipeline regulating valve, a fresh water pipeline regulating valve, switchingvalves of each cleaning group, a spraying mechanism and a cleaning indicator. The pressure, flow rate and temperature of cleaning liquid of the cleaning system are adjustable and controllable, and the stepped cleaning control of medium pressure, low pressure, clean water, and hot water is realized; according to the characteristics of devices at each cleaning point and the characteristics of the contained materials, grouping and partitioning automatic cleaning control is performed; and the sewage treatment load is reduced, and the cleaning liquid enters the production system and is recycled. The cleaning system realizes the fixed-point and regular online cleaning of the production line equipment, solves the problem of deterioration of retained materials in the dead corners of the equipment, improves the level of lean management of the production line and product quality and safety control, saves cleaning water, reduces the cost of manual cleaning operations, and has achieved good application evaluation.