The invention discloses a vacuum removing mechanism for a medicinal plate with pills missed. The vacuum removing mechanism is characterized by comprising a suction box and a filter, the bottom of thesuction box is provided with a plurality of openings side by side, each opening is shielded by an independent movable baffle, movement of the baffle is pushed by an air cylinder, the filter is provided with a transverse hole, the middle portion of the hole wall of the transverse hole is provided with a front vent hole and a rear vent hole, the front vent hole communicates with a vacuum tube, and the rear vent hole communicates with the suction box through an air receiving pipe. Left and right filter rings are movably arranged in the transverse hole, front and rear feeding holes are formed in each filter ring; when the left filter ring is at the middle portion, a front filter hole and the rear feeding hole of the left filter ring are aligned at the front vent hole and the rear vent hole, the right filter ring communicates with a pill collecting box; and when the right filter ring is at the middle portion, a front filter hole and the rear feeding hole of the right filter ring are alignedat the front vent hole and the rear vent hole, and the left filter ring communicates with the pill collecting box. The vacuum removing mechanism can automatically recover other pills of the medicinalplate with the pills missed, and the labor intensity of workers is reduced.