The application relates to a 3D laser printing material and a preparation method therefor. The 3D laser printing material is prepared through firstly synthesizing nylon resin from branched-chain pentamethylene diamine, sebacate or dodecanedioic acid, carrying out modification by an extruding modification process, and then, carrying out a chemical powdering process. The 3D laser printing material has the advantages of moderate melting point, high toughness, low thermal shrinkage ratio, yellowing resistance, easiness in construction and the like.