The invention provides an operation strategy optimization method for a multi-energy complementary new energy power generation system. The operation strategy optimization method is executed in computing equipment, and comprises the following steps of acquiring operating parameters of a multi-energy complementary energy system, wherein the multi-energy complementary energy system includes a plurality of different types of new energy power generation systems; respectively setting operation modes of various new energy power generation system; and under the constraint of the set operation modes andthe operating parameters, respectively determining the optimal output power of a plurality of new energy power generation systems, wherein the optimal output power is the output power which maximizesthe operating income of the multi-energy complementary energy system. The invention further discloses the corresponding computing equipment.