The invention discloses a balance valve and safety valve set used for a buoyancy regulation system. The balance valve and safety valve set comprises a valve body, a balance valve assembly, a safety valve assembly and a valve deck. The balance valve assembly is arranged at the position of a first through hole of the valve body. The balance valve assembly comprises a first valve rod, a first valve seat, a screw plug, a first valve element assembly and a first spring. The safety valve assembly is arranged at the position of a second through hole of the valve body. The safety valve assembly comprises a second valve rod, a second valve seat, a second spring seat, a second valve element assembly, a second spring, a sealing cover and a regulation threaded rod. An inner cavity of the valve deck communicates with a first passageway and a second passageway. A main valve cavity is formed by the inner cavity of the valve deck, the first passageway and the second passageway together. A first pipeline connector is arranged on the valve deck. A second pipeline connector, a third pipeline connector and a fourth pipeline connector are arranged on the valve body. The valve element assemblies in thebalance valve and safety valve set have an automatic aligning function, leakproofness is good, and meanwhile by means of the effect of limiting spherical hinges, separation of the valve elements and valve rods is avoided.