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发明公开
CN110801471A 能够提高结肠癌和/或直肠癌免疫治疗效果的红枣加工品及其使用方法 无效 - 驳回

能够提高结肠癌和/或直肠癌免疫治疗效果的红枣加工品及其使用方法
摘要：
本发明公开了一种能够提高结肠癌和/或直肠癌免疫治疗效果的红枣加工品及其使用方法。本发明要求保护红枣加工品在制备强化免疫治疗结肠癌和/或直肠癌的产品中的应用；本发明还要求保护红枣加工品在制备能够提高PD-1/PD-L1抗肿瘤效果的产品中的应用；本发明还要求保护红枣加工品与PD-1/PD-L1抑制剂联用在制备能够提高PD-1/PD-L1抗肿瘤效果的产品中的应用。利用本发明提供的红枣加工品及使用方法，可使MC38结肠癌小鼠肿瘤较单纯使用PD-L1治疗的对照组显著减小。
摘要（英）：

The invention discloses a jujube processed product capable of improving colon cancer and/or rectal cancer immunotherapy effects and a using method thereof. The invention claims the protection of an application of the jujube processed product in the preparation of products for intensive immunotherapy of colon cancer and/or rectal cancer. The invention also claims the protection of an application ofthe jujube processed product in the preparation of products capable of improving the antitumor effects of PD-1/PD-L1. The invention also claims the protection of an application of the jujube processed product in combination with a PD-1/PD-L1 inhibitor in the preparation of products capable of improving the anti-tumor effects of PD-1/PD-L1. By using the jujube processed product and the using method provided by the invention, the tumor of MC38 colon cancer mice can be significantly reduced compared with the control group treated with PD-L1 alone.

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