The invention provides an SF6 substitute medium selection method based on environmental protection, and relates to the field of electrical technology. The method comprises the following steps: 1, determining a temperature environment and an inflation pressure range of an SF6 substitute medium; 2, calculating to obtain a liquefaction temperature corresponding to the SF6 substitute medium under thecorresponding inflation pressure according to a Riedel vapor pressure equation and a Raoult law; 3, according to the given range of the environment temperature of equipment operation, selecting an SF6replacement medium with the liquefaction temperature meeting the requirement; and 4, comparing the global warming potential values of the SF6 substitute media screened in the step 3 to obtain gas meeting conditions. The method is simple in calculation means, easy to operate and high in applicability, corresponding SF6 substitute gas can be selected according to different power equipment, use of SF6 can be greatly reduced, and the method plays a positive role in environmental protection.