利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN110812525A 脂肪干细胞外泌体的无菌胶原液及贴敷的制备方法 无效 - 驳回

  • 专利标题： 脂肪干细胞外泌体的无菌胶原液及贴敷的制备方法
  • 专利标题（英）： Preparation methods of adipose-derived stem cell exosome sterile collagen liquid and application thereof
  • 申请号： CN201911382525.5
    申请日： 2019-12-27
  • 公开(公告)号： CN110812525A
    公开(公告)日： 2020-02-21
  • 发明人: 张伟 , 胡大海 , 李超
  • 申请人： 张伟
  • 申请人地址： 陕西省西安市新城区幸福中路33号
  • 专利权人： 张伟
  • 当前专利权人： 张伟
  • 当前专利权人地址： 陕西省西安市新城区幸福中路33号
  • 代理机构： 郑州欧凯专利代理事务所
  • 代理商 樊晓坤
  • 主分类号： A61L15/32
  • IPC分类号： A61L15/32 ;  A61L15/40 ;  A61L15/42 ;  A61K8/98 ;  A61K8/65 ;  A61Q19/00
脂肪干细胞外泌体的无菌胶原液及贴敷的制备方法
摘要：
本发明公开了一种脂肪干细胞外泌体的无菌胶原液，由脂肪干细胞外泌体和无菌胶原液组成，每毫升无菌胶原液中含有0.5-0.8mg外泌体。其制备方法为：在无菌环境下，将脂肪干细胞外泌体和无菌胶原液混合并搅拌均匀，低温保存即可。本发明还公开了脂肪干细胞外泌体的无菌胶原液贴敷的制备方法，无菌条件下将脂肪干细胞外泌体的无菌胶原液压合在两块无纺布中间，再装入铝箔袋中封口低温保存即可。本发明通过将脂肪干细胞外泌体和无菌胶原液相结合制得脂肪干细胞外泌体的无菌胶原液，能够充分发挥两者的作用，对皮肤损伤修复以及创面修复有更好的治疗效果，且能够缩短创面愈合时间。
摘要（英）：

The present invention discloses adipose-derived stem cell exosome sterile collagen liquid. The adipose-derived stem cell exosome sterile collagen liquid consists of adipose-derived stem cell exosomesand sterile collagen liquid, wherein each milliliter of the sterile collagen liquid contains 0.5-0.8 mg of the exosomes. The preparation method comprises the following steps: mixing the adipose-derived stem cell exosomes and the sterile collagen liquid in a sterile environment, and conducting uniform stirring and storage at low temperature. The present invention also discloses a preparation methodof an application of the adipose-derived stem cell exosome sterile collagen liquid. Under a sterile condition, the adipose-derived stem cell exosome sterile collagen liquid is pressed between two non-woven fabrics, and then the application is filled into an aluminum foil bag to be sealed and preserved at low temperature. The adipose-derived stem cell exosome sterile collagen liquid is prepared bycombining the adipose-derived stem cell exosomes with the aseptic collagen liquid, can fully play roles of the adipose-derived stem cell exosomes and the aseptic collagen liquid, has better treatmenteffects on skin injury repair and wound repair, and can shorten wound healing time.

0/0