A sealing structure for fuel cell, includes membrane electrode, flow guided plate, seal ring. The said membrane electrode is set in the middle, the said flow guided plate is pressed at the both sides of the membrane electrode, the said seal ring is set at the press-fit surface of the flow guided plate and membrane electrode, the said membrane electrode includes active region and sealing region, the sealing region is set around the active region, the said active region includes proton exchange membrane, cellularity supporting materials, catalyst, the catalyst attach¿ªs the cellularity supporting materials and is pressed at the both sides of the proton exchange membrane, the said sealing region consists of proton exchange membrane or cellurity supporting material or hot cement plastic or thermoset rubber and resin, the thickness of sealing region is the same with the thickness of active region.