Disclosed is a method of consolidating railway or highway bridge in subsidence area to resist large deformation, which is mostly suitable for treating water traffic facilities with uneven large extent subsidence in subsidence area. The invention adopted box-shaped anti-deformation structure access bridge, and according to the water surface width, one or more separate box-shaped anti-deformation structure bridge combination is applied, which can effectively resist effects of unequal subsidence, curvature distortion and such big earth surface distortions of picking area, guarantee normal transportations of railway or highway during surface subsidence, and can guarantee normal transportations of railway or highway when the accumulative surface subsidence is 0-8 meter. Said method saves land resources for changing ways and rivers greatly with simplicity and good effect, does not affect productions of coal mine.