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CN1931818B 一种合成辅酶Q10的方法 失效 - 权利终止

一种合成辅酶Q10的方法
摘要：
本发明涉及一种合成辅酶Q10的方法。该方法是以辅酶Q0氢醌和含量不低于95％的异癸十异戊二烯基醇为原料，经脱水后，在无氧环境中经三氟甲磺酸及其金属盐催化，室温条件下缩合反应，得到辅酶Q10氢醌，反应物不需要任何处理，与过氧化氢、三氯化铁的水溶液进行氧化反应，得到辅酶Q10粗产物，粗产物经丙酮结晶处理，得到辅酶Q10黄色粉末，含量＞99％，收率＞65％(以异癸十异戊二烯基醇计)。本发明操作简便，产品易于提纯，收率高，反应条件温和，生产过程安全可控，具有工业化生产价值。
摘要（英）：

The coenzyme Q10 synthesizing process with coenzyme Q0 hydroquinone and isodecyl alcohol deca-isopentyl alcohol of purity not lower than 95 % as material includes dewatering and condensation reaction at room temperature under the catalysis of trifluoro methane sulfonic acid in no oxygen environment to obtain coenzyme Q10 hydroquinone, the oxidation of the reacted product without passing through any treatment with hydrogen peroxide and water solution of ferric trichloride to obtain crude coenzyme Q10 product, and crystallization of the crude coenzyme Q10 product in acetone to obtain yellow coenzyme Q10 product powder in content over 99 % and yield over 65 %. The present invention has simple operation, easy purification of the product, high yield, mild reaction condition, safe and controllable production process and industrial production value.

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