A compound represented by the structural formula and pharmaceutically acceptable salts and solvents thereof are disclosed, wherein: the single-dashed line between the ring carbons to which R<10> and R<34> are attached represents either a single bond or a double bond; the double-dashed line between X and the carbon to which Y is attached represents either a single bond or an absent bond; X is -O- or -NR<6>- when the double-dashed line represents a single bond; X is H, -OH or -NHR<20> when the double-dashed line represents an absent bond; and other parameters are as defined herein. Also disclosed are pharmaceutical compositions and combinations containing said compounds and their uses as thrombin receptor antagonists and binders to cannabinoid receptors.